Spectrophotometric Determination of Haloperidol in Pure Form and Pharmaceutical Formulation using Calcon and Amido Black
Research Journal of Pharmacy and Technology / 8 - مارس - 2017
Two simple, rapid and sensitive spectrophotometric methods have been developed for determination of Haloperidol (HP) in pure form and pharmaceutical formulations. A good sensitive colour reaction has been developed, based on the fact that Haloperidol (HP) reacts with a Calcon (Cal) or Amido Black (AB), to form an ion-association complex in acidic buffer solution, giving pink color with Calcon and blue color with Amido Black, the absorbance of chloroform extracted complexes were measured at 531 nm and 626 nm respectively. The effects of analytical parameters on the reported systems were investigated.
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Quantitative determination of albendazole forced degradation percentages by densitometric thin layer chromatographic method
Research Journal of Pharmacy and Technology / 3 - يوليو - 2020
Simple densitometric thin layer chromatographic method has been applied in this study to proceed forced degradation test of albendazole by subjecting drug to acidic, alkaline, oxidative, thermal, and photolytic conditions, and determine the degradation percentages of albendazole in these conditions after 1, 2, 4, and 6 hrs.