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The Detection of HER2 Gene Amplification in Breast Cancer by upQMPSF

The amplification of human epidermal growth factor receptor 2 (HER2) gene in breast cancer identifies patients eligible for Trastuzumab therapy. immunohistochemistry (IHC) and/or fluorescent in situ hybridization (FISH) are the only FDA approved techniques for evaluating HER2 status. However, Interobserver variability is still a dilemma

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