Synergistic effect of Thymbra spicata L. extracts with antibiotics against multidrug- resistant Staphylococcus aureus and Klebsiella pneumoniae strains
Iranian Journal of Basic Medical Sciences / 19 - November - 2016
To evaluate the in vitro interaction between different extracts of Thymbra spicata L. and certain antimicrobial drugs of different mechanisms, including ampicillin, cefotaxime, amikacin and ciprofloxacin.
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Antibacterial Activity of Asphodelin lutea and Asphodelus microcarpus Against Methicillin Resistant Staphylococcus aureus Isolates
International Journal of Pharmacy and Pharmaceutical Sciences / 15 - December - 2016
Objective: the present study aimed at evaluation of antibacterial activity of wild local Asphodelus microcarpus and Asphodeline lutea against methicillin resistant Staphylococcus aureus (MRSA) isolates.. Methods: Antimicrobial activity of the crude extracts was evaluated against MRSA clinical isolates using agar wells diffusion. Determination of minimum inhibitory concentration( MIC)of methanolic extract of two studied plants was also performed using tetrazolium microplate assay
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Prasugrel, being a potent platelet aggregation inhibitor, is used widely around the world to reduce cardiovascular risks in patients with stroke, myocardial infarction, and atherosclerosis. The aim of this review firstly to focus on a comprehensive update of chromatography determination of Prasugrel and its metabolites in human plasma, and in pharmaceutical preparations. It has been described using TLC, HPLC/MS, RP-HPLC, and UV methods. Secondly to localize the chromatographic conditions for separation and quantification. This review provides detailed information on separation conditions for Prasugrel alone, with Aspirin, and in the presence of its related compounds
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Isolation and Ultra-Purification of Oleic Acid Extracted from Olive Oil Using Urea Crystallization
Research Journal of Pharmacy and Technology / 24 - March - 2018
Oleic acid is an omega-9 fatty acid that is found naturally in many vegetable sources and animal products The major component in olive oil is the triglyceride esters of oleic acid. This triglyceride is one of the sources of good cholesterol
Determination of Prasugrel Hydrochloride in Bulk and Pharmaceutical Formulation Using New Ion Selective Electrodes
Research Journal of Pharmacy and Technology / 22 - September - 2018
The construction and performance characteristics of Prasugrel hydrochloride (PRS) selective electrodes were developed. Electrodes were based on the incorporation of PRS with pairing agents, Ammonium Molybdate (MOL) and Nessler reagent (NES).
GC-MS Analysis of European Mistletoe (Viscum album L.) Plant Grown at Syrian Coastal Area
Asian Journal of Chemistry / 29 - April - 2020
In this study, efforts were made to isolate phtochemicals from European mistletoe (Viscum album L.) using hot (Soxhlet) and cold (magnetic rotation) extraction methods. The dried Viscum album L. (10 g) were extracted exhaustively by Soxhlet with methanol and dichloroethane solvents. Subsequently, 1 μL of sample was utilized for GC/MS analysis, which exhibited 50 peaks of phytoconstituents in the range of 0.12-22.04%.
Quantitative determination of albendazole forced degradation percentages by densitometric thin layer chromatographic method
Research Journal of Pharmacy and Technology / 3 - July - 2020
Simple densitometric thin layer chromatographic method has been applied in this study to proceed forced degradation test of albendazole by subjecting drug to acidic, alkaline, oxidative, thermal, and photolytic conditions, and determine the degradation percentages of albendazole in these conditions after 1, 2, 4, and 6 hrs.