COVID-19 is an illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which belongs to beta-coronaviruses. SARS-CoV-2 has caused a pandemic since it was reported in December 2019 in Wuhan, China. The data about the severity of this viral infection in children increased gradually with the appearance of the new variants, but they are still limited compared to the data of adults. Generally, Children with COVID-19 are asymptomatic or have mild symptoms. The most common symptoms include fever, headache, cough, rhinorrhea, sore throat, myalgias, fatigue and gastrointestinal manifestations.